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This can support investigation of how energy expenditure, substrate use, and feedback signaling interact

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SLU-PP-332's pharmacological positioning is that of a **synthetic agonist of all three paralogs ERRalpha, beta, gamma** (Estrogen-Related Receptors), orphan nuclear receptors discovered by Vincent Giguere in 1988

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However, despite being the largest study in this field to date, covering more than 3.5 million pregnancies, relatively few women used these drugs, and some estimates were imprecise

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In dermatology, tranexamic acid has gained attention because it appears to affect pigmentation pathways involved in melasma

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