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Subsequently, NP4-Cy7.5 was intravenously injected into BALB/c mice, and the biodistribution of nanoparticles in mice was observed using an in vivo imaging system (IVIS)

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with a mean increase of 8 points) and tirzepatide (SUMMIT), appears to be greater than what has been reported for other HFpEF trials investigating the benefits of angiotensin receptorneprilysin inhibitor (Paragon-HF), sodiumglucose cotransporter 2 inhibitors (EMPEROR-Preserved, DELIVER) and spironolactone (TOPCAT)

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The cellular and molecular origin of reactive oxygen species generation during myocardial ischemia and reperfusion