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What the biology reviewed in this article makes clear is that this framing has always been inadequate

However, even with a three medication regimen (RASi, SGLT2i, and nsMRAs), there is still undeniably room for improvement, because residual risk in diabetic still looms large

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You can take L-carnitine at night as long as it fits with your goals

Similarly, other previous studies found that retinal venular widening correlated with an increased risk of CKD progression in T2DM patients, highlighting the retina's predictive value (137, 138)