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The answer appears to be both, though the relative contributions remain unclear

Findings of NAD and glutathione changes are reported in genetic metabolic diseases as well as in degenerative, age-related diseases 1,2

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Digestive side effects of GLP-1s include nausea, bloating, vomiting, constipation, diarrhea, belching, indigestion and more, outlined in Figure 3 of this article and Table 2 of this article

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