Other contributors include faulty axonal transport, resulting in buildup of neurofilaments and synaptic breakdown (Taylor et al., 2016), and genetic mutationssuch as SOD1 (causing harmful protein accumulation), FUS (interfering with RNA handling), and TBK1 or OPTN (which impair the cell's waste disposal system known as autophagy
Nevertheless, without robust clinical evidence, healthcare professionals should approach patient reports of hiccups with appropriate clinical judgement, considering alternative causes whilst acknowledging the patient's experience
For instance, if you inject semaglutide once a week, you might rotate between the stomach, thigh, and upper arm (Mayo Clinic Diet) (Drugs.com)
Dermatol Ther
rs1171617 was also related to uric acid
This sends a signal of fullness to the brain, which in turn suppresses feelings of hunger