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Zhang AQ, Mitchell SC, Smith RL

Animal models of autism: a perspective from autophagy mechanisms

These estimates are general guidelines

Considering the positive impact of Nrf2 in ameliorating oxidative stress, a number of bioactive components that exert protective effect against APAP-associated hepatotoxicity have been identified and reported, including caffeic acid that activates the Keap1-Nrf2 antioxidant defense system (Pang et al., 2016), carnosic acid that promotes nuclear translocation of Nrf2 ( via AMP-activated kinase/Akt/glycogen synthase kinase 3 pathway (Wang et al., 2016)

34 Another study indicated that the incidence of sucrase-isomaltase deficiency, which leads to sucrose intolerance, ranges from 0.2% in North America to 10.0% in Greenland Inuit populations