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Others may choose the combination during times of increased physical demand

Rao H et al

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REDEFINE 1 Effect of CagriSema in Adults With Overweight or Obesity

Finally, a four-year, multicenter, clinical trial in 421 diabetic patients with distal symmetric sensorimotor polyneuropathy found no difference between oral administration of 600 mg/day of lipoic and placebo on the primary endpoint, a composite score that assessed neuropathic impairment of the lower limbs and nerve conduction (78)