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Studies have documented its capacity to stimulate collagen and glycosaminoglycan synthesis, accelerate wound healing, promote angiogenesis, exert antioxidant and anti-inflammatory effects, and modulate the expression of genes involved in tissue repair and regeneration

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L-carnitine supplementation significantly improved LVEF (MD = 1.64, 95% CI 0.103.17, p = 0.04), with low heterogeneity ( I 2 = 37%)

493,494 Two isoforms of GDI are present: GDI1 encodes for GDI, principally enriched in the brain, whilst GDI2 encodes for GDI that is ubiquitously expressed

The study was a randomized, double-blinded, placebo-controlled, crossover trial---the gold standard for scientific trials

[4] Ghrelin was later identified as a natural acylated peptide ligand for this receptor