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Exenatide extended-release (Bydureon/BCise) carries a boxed warning regarding thyroid C-cell tumors based on rodent studies and is contraindicated in patients with a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2

Human data are limited and mixed: Clinical studies have largely assessed safety and metabolism, while weight-related outcomes were modest and inconsistent

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It is safety. A History of Eating Disorders This section deserves nuance, not a blanket statement

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B12 also supports metabolism