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Clinical data shows semaglutide achieves HbA1c reductions of up to 1.7%2.0%, with weight loss exceeding 10% body mass in nearly 45%61% of patients, significantly outperforming earlier therapies

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Common side effects include water retention, increased appetite, tingling in the hands, and potential cortisol or prolactin elevation at higher doses

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Semaglutide, a long-acting glucagon-like peptide-1 receptor agonist (GLP-1 RA), represents a major advancement in medical obesity management due to its substantial and durable weight-loss efficacy demonstrated across diverse populations[6]

This application remains experimental