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In cartilage tissues of the OA knee, upregulation of inflammation-related proteins is accompanied by the downregulation of GLP-1R and PKA/CREB pathways

The mechanism likely involves correction of oxidative stress and modulation of glutamate signaling via the cystine-glutamate antiporter (system Xc-) [73][74]

A., Wilcken, B., Hoffmann, G

Excessive incidence of stroke in Iran: evidence from the Mashhad Stroke Incidence Study (MSIS), a population-based study of stroke in the Middle East

Your body naturally produces and uses peptides to send signals between cells

PMID: 20034526 Evans-Brown M, McVeigh J, Perkins C, Bellis MA