The synergy rationale, and its status The pharmacological argument for combining these two is coherent on paper
Gastrointestinal Effects of GLP-1 Receptor Agonists: Mechanisms and Clinical Implications
In electron-transfer reactions, dinucleotides are recycled back and forth between their oxidized forms (NAD + and NADP + ) and reduced forms (NADH and NADPH)
High-dose B12 supplements, even 1,000 mcg daily, are generally safe because the body uses what it needs and excretes the rest
Knop FK, Aroda VR, do Vale RD, Holst-Hansen T, Laursen PN, Rosenstock J, et al
In view of lack of data against its use after transplantation the KDIGO work group suggests use of metformin in the transplant population using the same approach as for CKD group