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When researchers strapped activity monitors on adults instead of asking them to self-report, fewer than 5% actually hit the basic guideline of 150 minutes of moderate activity a week (Troiano, Medicine & Science in Sports & Exercise, 2008)
Though these GLP1-class drugs seem to be well tolerated by the majority of patients, long-term studies are still needed
On top of increasing the median lifespan of mice and worms, spermidine has protective effects on the heart and a beneficial impact on age-associated diseases like cancer and neurodegeneration in some animals