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Four proline residues, including an unusual triple-proline sequence, give BPC-157 exceptional stability

The 2011 Pavicic randomized controlled trial in Journal of Drugs in Dermatology is the foundational study

Important context: this is early data and should be interpreted cautiously

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Under physiological conditions, ROS are generated in the heart mainly from the mitochondrial electron transport chain, nitric oxide synthases (NOS), NADPH oxidases (NOX), and xanthine oxidase (XO) in small quantities [7, 8]