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Furthermore, both of them have serious side effects, with each carrying a boxed warning regarding the potential risk of thyroid cancer

Earlier this month, (June 2025), Novo inked a deal worth up to $815 million with Deep Apple Therapeutics, a South San Francisco-based company specializing in small-molecule drug discovery to discover, develop, and commercialize oral small-molecule therapeutics directed at a non-incretin G protein-coupled receptors (GPCR) target for cardiometabolic diseases, including obesity, in a deal worth up to $812 million

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In human patients, glutathione has been used as a treatment for chronic liver disease, mostly by intravenous administration

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Currently in phase 3 clinical trials and due to be approved in 2026, orforglipron is being closely studied for its effectiveness and affordability