Possible Complications from Untreated Strep When left untreated, strep throat can lead to complications, though they are uncommon with access to modern medical care
doi: 10.1038/362075a0 52 HanWNHlscherCYuanLYangWWangXHWuMNet al
In this prospective, double-blind trial in 304 patients with T2DM and coronary artery disease, subjects randomized to metformin or glipizide for 3 years obtained similar glycemic control (average A1C of 7.0% and 7.1%, respectively)
Therefore, GLP-1 analogues have been found to have several non-glycaemic effects including improved blood pressure through arterial vasodilation and increased renal natriuresis and reduced appetite via delayed gastric emptying and centrally mediated satiety within the hypothalamus
But it can also lead to unexpected or unadvertised side effects
It can matter but mostly within limits