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Additionally, immune cells such as macrophages and neutrophils produce free radicals to combat pathogens in a process known as the respiratory burst [23]

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Similar results were found in a clinical study in patients with T2DM, where administration of liraglutide, but not metformin, increased the relative abundance of Akkermansia , which is often associated with the improvement of gastric mucosa and also becomes severely depleted in diabetic patients [115]

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