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In the brains of the treated mice, some microglia switched from attack (a mode known as M1) to a more neutral state (M2)
For example, 0.25 mL is 25 units
Nausea Vomiting Diarrhea Abdominal pain Constipation Dyspepsia (indigestion) Decreased appetite Headache Fatigue Pancreatitis Gallbladder disease (cholelithiasis, cholecystitis) Acute kidney injury (usually from dehydration via GI fluid loss) Hypoglycemia (mainly when combined with insulin or a sulfonylurea) Diabetic retinopathy complications Increased resting heart rate Thyroid C-cell tumours (boxed warning
Another way of action for gut-derived GLP-1 includes indirect signaling via the vagus nerve
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