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It has to distinguished that the replacement therapy should be only undertaken to restore the physiological levels, never to exceed physiological ranges

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This underscores the importance of optimizing antioxidant responses to enhance the efficacy of corticosteroids [81]

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[4] It is suggested that upon binding to the GHRH receptor, Tesamorelin & Mod GRF may induce conformational changes in the receptor structure, potentially activating intracellular signaling pathways