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4 Mechanisms of Acetaminophen & NSAID Toxicity Despite similarities in activity, the potential toxicities of acetaminophen and NSAIDs arise from different mechanisms

10.1142/S0192415X08006259 97 ShishodiaS.SethiG.AggarwalB

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These in-organ changes in energy metabolism are also reflected in the plasma metabolome after ischemic AKI, which is characterized by the depletion of numerous amino acids and energy substrates 6

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