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Synthetic form: While DSIP occurs naturally in small amounts, the versions used in research and supplementation are synthetically produced to mimic the bodys own peptide

Conversely, there could be lack of elements needed to maintain OL and myelin integrity (e.g., sources of energy, lipids) 19

Are there cardiovascular effects, positive or negative, that only manifest over extended periods

doi: 10.1016/j.hsr.2025.100237 88

Effect of combined administration of vitamin D3 and vitamin K2 on bone mineral density of the lumbar spine in postmenopausal women with osteoporosis

It is important to note that the micro-CT data identified elevated levels of the bone formation marker, osteocalcin, in KIR mice