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Anisimov VN, Mylnikov SV, Khavinson VK
Springer Berlin
The first dose is usually 1000 mcg weekly
Identifying stressors and implementing management strategies supports metabolic goals
The top dose produced 20.9% average weight loss over 72 weeks and 20.2% in a direct comparison with semaglutides 13.7%. Its second receptor, GIP, separates tirzepatide from approved single-receptor GLP-1 drugs and helps explain the larger population-level weight loss. That 20.9% came from participants averaging about 105 kg at a BMI of 38, most of whom were sedentary
These dietary choices limit natural sources of B12 to animal products, leading to deficiencies in up to 90% of people adhering to these diets
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