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Common cleavable linkers include acid-cleavable linkers (e.g., hydrazone), pH-sensitive linkers, enzyme-cleavable linkers (peptide linkers, such as Cathepsin B-sensitive sequences), disulfide linkers, and redox-sensitive linkers triggered by reductive environments

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Legal Status Like many experimental peptides, Dihexa is not FDA-approved and has never been advanced into formal human clinical trials

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