Glutathione S-transferase T1 (GSTT1) null polymorphism, smoking, and their interaction in coronary heart disease: a comprehensive meta-analysis

You may be a candidate if you: Have a BMI in the overweight or obese range, especially with weightrelated medical conditions Have tried lifestyle changes and previous weightloss efforts without lasting success Are willing to pair medication with changes in nutrition, activity, and daily habits Do not have certain contraindications, such as a history of specific thyroid cancers or multiple endocrine neoplasia type 2 (MEN2) Are not pregnant or breastfeeding and are not planning pregnancy while using the medication During your visit, your doctor will review: All current medications and supplements Personal and family medical history Prior reactions to similar medications Your specific health priorities (better mobility, improved labs, less medication, etc.) Only if the potential benefits outweigh the risks will tirzepatide be recommended as part of your plan
Nutrition: Keep protein intake adequate and total calories aligned with your body-composition goal
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As long as they remain effective, well-tolerated, and there are no adverse events, GLP-1 agonists can be used for long-term weight loss management
The study protocol was approved by the regional ethics committee