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The 1 mg dose has direct human diabetes-trial activity. Below 1 mg is more speculative

A total of 260 CPPs were synthesized using standard fluorenylmethoxycarbonyl solid-phase peptide synthesis (Fmoc-SPPS) on 2-chloro-trityl chloride resin with protected amino acids

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In addition, GSH depletion induced SIPS, as evidenced by increased percentage of the senescence-associated -galactosidase-positive cells, increased senescence-associated heterochromatin foci (SAHF), as well as cell cycle arrest at the G1 phase