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One of the biggest hurdles people face when trying to lose weight is food noise
2015;308:F87887
What makes GLP-1 medications revolutionary is their ability to address the biological drivers of obesity not just willpower or caloric math
GcgR agonism drives hepatic fatty acid oxidation and thermogenesis, adding an energy-expenditure mechanism on top of the appetite-suppression and insulin-secretion mechanisms of GLP-1R/GIPR
B.BadenochJ
Interestingly, Kanbay and colleagues (2007) found that allopurinol at 300mg/d over 3 months improved GFR, uric acid and C-reactive protein levels but made no change to proteinuria [169]
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