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The affected regions primarily include fibers within the corona radiata and internal capsule, such as the corticospinal tract and thalamic radiations Note
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Tirzepatide (Mounjaro/Zepbound) Potential: Newer research reviews (2025) have highlighted Tirzepatidewhich targets both GLP-1 and GIP receptorsas a potential "disease-modifying" therapy
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Onofrj M, Fulgente T, Melchionda D, et al
Although ACG normally codes for threonine, in the PRPS1L1 mRNA this alternative start codon directs the initiator methionine for the encoded protein
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