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Based on this functional interpretation, what are the underlying molecular/cellular mechanisms that represent possible pharmacological targets

Nevertheless, more data from adequately powered human studies are required for further evaluation of the impact of gut microbiota on thyroid diseases and the potential for possible therapeutic interventions

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Taking an acid-blocking medication for several years can significantly diminish a persons absorption of vitamin B12, leading to symptoms of fatigue, neuropathies, and weakened immunity

And thats the kind of danger zone that the female athlete triad is all about: when chronic energy deficiency becomes too much and suppresses reproductive function and suppresses the formation of bone. That leads to low estrogen levels too