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Ongoing studies continue to examine cellular communication, angiogenic signaling, extracellular matrix remodeling, connective tissue physiology, and tissue homeostasis

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The accumulation of advanced glycation end products (AGEs) can also induce apoptosis (cell death) in fibroblasts, resulting in a significant loss of hyaluronic acid, collagen, and elastin

Protein kinase CK2: structure, regulation and role in cellular decisions of life and death