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Notably, CMS will treat all formulations of semaglutide as a single product for negotiation purposes (regardless of brand name, dosage form or approved indication), potentially leading to more uniform and substantial price reductions across these therapies

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Most are gastrointestinal, including nausea, vomiting, diarrhea, constipation, or abdominal discomfort, but some symptoms may signal dehydration, kidney stress, gallbladder disease, pancreatitis, hypoglycemia, or another problem that requires medical evaluation

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The results of comparison of other indices are shown in Table 10-12