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Similar clinical symptoms are found in individuals with hereditary IF deficiency (also called congenital pernicious anemia) in whom the lack of IF results in the defective absorption of vitamin B 12

1 2 3 "What Are the Signs and Symptoms of Pernicious Anemia?"

They may arrange blood tests to evaluate: Inflammatory markers (ESR, CRP) to detect active inflammation Rheumatoid factor and anti-CCP antibodies if inflammatory arthritis is suspected Full blood count to assess haematological response to B12 treatment Thyroid function tests , as thyroid disorders commonly coexist with B12 deficiency Note that serum B12 levels are not typically measured to assess treatment adequacy once replacement therapy has begun, as they may not reliably reflect tissue stores

Days 128 in animal research : mouse studies reported metabolic and fat-mass changes during this window