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Key Facts Targeting Wanting, Not Just Feeling: While scientists knew GLP-1 drugs affected the hindbrain to signal fullness, this study found they also engage a circuit linking the central amygdala to dopamine neurons

These results held true across diverse patient populations, including those with existing type 2 diabetes and those with insulin resistance alone

Medications that mimic this hormone help enhance these natural signals, which can lead to reduced appetite, improved blood sugar control, and better portion awareness

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10.1016/j.cmet.2019.03.010 Cell Metab