People with Absorption Issues : People with Crohns disease or celiac disease may not be able to absorb B12 from food, so injections are a better option

It includes 1-5 intramuscular or subcutaneous injections of 1000 mcg crystalline cyanocobalamin daily, followed by oral doses of 1000-2000 mcg/day Parenteral administration should be reserved for those with significant neurological symptoms NICE guideline: Vitamin B 12 deficiency in over 16s: diagnosis and management: Malabsorption as the confirmed or suspected cause of vitamin B 12 deficiency: Offer replacement to people if: lifelong intramuscular vitamin B12 Autoimmune gastritis is the cause They have had a total gastrectomy They have had a complete terminal ileal resection If the person has a vitamin B 12 deficiency because of malabsorption that is not caused by autoimmune gastritis, or a total gastrectomy or complete terminal ileal resection (for example, malabsorption caused by coeliac disease, partial gastrectomy or some forms of bariatric surgery): Offer vitamin B 12 replacement and Consider intramuscular instead of

Plus, the symptoms of low B12 can be very subtle, or they may be confused for symptoms of other conditions
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In two trials employing 1000 g/day oral vitamin B 12 , there was no clinically relevant difference in vitamin B 12 levels when compared with IM vitamin B 12
They can also recommend treatments for specific side effects where necessary