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For severe deficiency, the AAFP recommends loading doses typically daily or every other day for one to two weeks followed by monthly maintenance injections
K.KwakK.et al (2019)
This suggests a very good safety and tolerability profile indistinguishable from placebo in those trial settings
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SOFIA R.B
The D form of carnitine, on the other hand, is biologically inactive and isn't sold as a supplement
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