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Minimum side effect disruption

One study examining the effects of the GLP-1 liraglutide, for example, found that the medication improved insulin sensitivity within two weeks, prior to weight loss, in people who have obesity and prediabetes, but other research has found that GLP-1s only have minimal direct benefits on insulin sensitivity

Z., & Algarni, A

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The summary is provided in Tables 13

We did not include individuals treated with insulin alone as an active comparator as it would introduce a significant amount of bias with the lack of a codable index event (i.e