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The pivotal STEP 1 trial, published in The New England Journal of Medicine in February, included 1,961 adults without diabetes who had obesity or overweight with a weight-related comorbid condition
Orforglipron from Eli Lilly is a non-peptide, small-molecule GLP-1 agonist designed as a once-daily oral pill
Farnesoid X receptor interacts with cAMP response element binding protein to modulate glucagon-like peptide-1 (736) amide secretion by intestinal L cell
10.1016/j.celrep.2021.109718 121 LiuR.WangJ.LiangS.ZhangG.YangX
Gavezzotti A
Plasma advanced glycation end products are associated with incident cardiovascular events in individuals with type 2 diabetes: a case-cohort study with a median follow-up of 10 years (EPIC-NL)
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