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However, therapeutic doses for treating deficiency range from high-dose oral supplements (1,0002,000 g daily) to intramuscular injections of 1 mg, particularly for pernicious anaemia or malabsorption conditions
In addition, B12 must be activated in your body (through a methylation process) in order to be used correctly
These factors suggest starting slightly higher than the minimum effective clinical dose to account for real-world variability
These are then mixed with potassium cyanide, sodium nitrite, and heat to produce cyanocobalamin, a stable crystalline molecule centered around a cobalt atom
J.et al (2018)