I think the most mysterious thing about these drugs is their effect on the brain
Rogers-Bennett, L., Dondanville, R
With a mature regulatory environment and steady product launches, North America continues to be the epicenter of market leadership
By improving the health of the brain's vasculature and reducing inflammatory responses, GLP-1R agonists may help preserve cognitive function in individuals with metabolic disorders or neurodegenerative conditions
Trulicity is clinically similar to Ozempic (both are GLP-1 receptor agonists), though head-to-head trials show semaglutide produces slightly greater A1C reduction and weight loss (Nauck et al., Lancet Diabetes & Endocrinology 2021)
But spotting the symptoms early can help prevent these complications developing