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FIGURE 4 (B) Ferrous iron could be delivered to the intracellular bacterial vacuole via inward FPN transportation, eventually inducing ferroptosis-like death of bacteria, which assists killing bacteria of macrophages ( Commonly, 15-lipoxygenases (15LOXes) can induce ferroptosis by catalyzing lipid peroxidation ( P
Myeloperoxidase produces nitrating oxidants in vivo
& Fang, J
Compounded drugs are not FDA-approved
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