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Arginine starvation kills tumor cells through aspartate exhaustion and mitochondrial dysfunction

Dogs under higher physiologic demandolder dogs, dogs recovering from illness, or dogs with chronic inflammatory conditionsare often the ones owners think about first

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Taken together, these observations support a model in which AP2 likely cooperates with the TRIM37TRIM28 complex at a subset of loci, while additional yet-to-be-identified factors may also contribute to targeting or stabilizing the complex at other sites

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