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Sources Sikiric P, et al

Blood tests can show if you lack vitamin B12

FDA Guidance for Industry: Human Growth Hormone and Related Biologics

Practice guideline update summary: Pharmacologic treatment for pediatric migraine prevention: Report of the Guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology and the American Headache Society

That idea is an extrapolation from rat data

Typical experimental endpoints include measures of collagen and extracellular matrix protein expression, cell migration rates, cytoskeletal organization, and transcriptional changes in genes related to tissue structure and repair, depending on the model