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Apart from the above, this study also showed that TMAO was closely related to the CHA2DS2-VASc score, a traditional embolization scoring system that is widely applied to assess the risk of subsequent embolism and to guide anticoagulant therapy in AF, 53 and pointed out that elevated TMAO played a vital role in the identification of embolism risk for those with low-risk scores

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GLP-1 is secreted primarily by L-cells in the distal small intestine and colon