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Methods Sixty rats were randomly divided into six groups: control, SM-treated (200 mg/kg body weight), SM-PNPs-treated (200 mg/kg body weight), HFD-treated, and two combination groups receiving HFD along with either SM or SM-PNPs (200 mg/kg body weight) for 5 weeks during the final phase of a 20-week HFD feeding period

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While O 2 itself is not directly microbicidal, it drives critical ionic fluxes that alkalinize and hypertonify the phagosomal lumen