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1 Smaller amounts of GLP-1 are also produced by neurons in the nucleus tractus solitarius (NTS) of the brainstem, thus highlighting its dual role in both peripheral and central metabolic regulation
Using a model of tauopathy in transgenic P301S mice, GLP-1RA semaglutide has been shown to reduce hyperactivity and cognitive decline
Exendin-4 is in many ways similar to the human hormone GLP-1, which increases insulin production in the pancreas
the measure is co-financed with tax funds on the basis of the budget passed by the Saxon state parliament (to M.F.), Deutsche Forschungsgemeinschaft (FE 1236/5-1 to M.F.) and Bundesministerium fr Bildung und Forschung (01EJ2205A, FERROPath to M.F.)
J Neurol 270(2):851863 Wharton S et al (2022) Gastrointestinal tolerability of once-weekly semaglutide 2.4 mg in adults with overweight or obesity, and the relationship between gastrointestinal adverse events and weight loss