While the mechanisms by which GLP1RAs lower food intake and aid weight loss have not been fully elucidated, GLP1RAs are known to directly interact with GLP-1 receptors in the circumventricular organs of the hypothalamus, the hindbrain and certain regions of the brain adjacent to ventricles that are considered to promote satiety and weight loss (36)
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This raises questions about the quality of care and the ability of these providers to handle the potential side effects of GLP-1 drugs
1 2 The American Journal of Clinical Nutrition
Semaglutide is the active ingredient in three drugs currently approved by the Food and Drug Administration (FDA)