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All authors reviewed and approved the final version of the manuscript

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Although astrocytes were also altered and may contribute to this process, the present study primarily focused on defining the causal role of microglial lipotoxicity, thereby providing a basis for future investigation of glial crosstalk

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4, the modified GPx-DTNB assay exhibits a linear response to GPx activity within the concentration range of 21000 units per liter (U/L), with an excellent correlation coefficient ( r = 0.999)