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Off-label prescribing is a common and legal practice where a medication is used for a purpose other than its FDA-approved indication, based on a physicians professional judgment and available scientific evidence

Who Retatrutide Is For and Who Should Avoid It Retatrutide is currently studied in adults with obesity, adults with type 2 diabetes, and adults with weight-related conditions like knee osteoarthritis, sleep apnea, and metabolic dysfunction-associated steatotic liver disease (MASLD)

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FDA-approved indications: Ozempic and Rybelsus are approved specifically for type 2 diabetes management and should not be prescribed for weight loss alone, despite the weight reduction commonly observed with these medications

Damage to the protective lining of the blood vessels ensues, as well as pathologic changes to kidney cells and kidney function

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