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The medication structure includes a fatty acid chain that allows it to bind to albumin in the bloodstream

It also tends to improve over time due to the body's adaptation to the drug

Addict Biol 21:422437 Wang W, Volkow ND, Berger NA et al (2024) Associations of semaglutide with incidence and recurrence of alcohol use disorder in real-world population

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PLoS ONE 8 , e61803 (2013)

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