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Diabetes Care 37 , 30163024 (2014)

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2.5.2 cDNA synthesis and RT-qPCR Reverse transcription was conducted with 40 ng of RNA per sample using the Reverse Transcription Master Mix Kit (Fluidigm Corporation, San Francisco, California, USA), following the manufacturers instructions

Early human trials with single subcutaneous doses of SAR441255 in healthy subjects demonstrated improved glycemic control during a mixed-meal tolerance test, while also being well-tolerated