In experimental models, suppression of spermatogenesis in the testes and degeneration of primordial follicles and granulosa cells in the ovaries are considered hallmark features of platinum-induced gonadotoxicity.8 Chemotherapeutic agents have been shown to deplete intracellular Glutathione (GSH), one of the major endogenous antioxidants, while simultaneously increasing Myeloperoxidase (MPO) activity, an indicator of inflammatory response, and elevating Malondialdehyde (MDA), a marker of lipid peroxidation.9 Co-administration of antioxidants during chemotherapy has therefore been proposed as a strategy to mitigate oxidative stress-induced tissue injury and improve therapeutic tolerance
The current findings are supported by previous studies 73,75
In the more common relapsingremitting form of MS, if an ongoing acute/adaptive immune response were the primary driver of later progression, atrophy and disability, it would stand to reason that there should be a strong correlation between inflammatory relapses and disability throughout the disease course
doi:10.1007/978-94-007-5787-5_1
Your LAF Prevention Protocol calls for dietary supplementation with L-Carnitine, and Alpha Lipoic Acid, along with CoQ10, Magnesium and Hawthorne, to help enhance the mitochondria function
He and patient advocate David Roth recently gave a presentation about how Dr